The two couldn’t have been further apart and it seemed unlikely that they could ever be friends.

Callie developed a camaraderie with Derekwhile operating on his million-dollar hand.

Teddy was at the time just coming to the realization that Owen had chosen Cristina over him.

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Teddy and Arizona’s friendship didn’t last too long as Teddy moved to Germany.

Miranda never minced words when it came to Derek and the latter seemed to actually appreciate her fearlessness.

Gradually,a beautiful friendship arose between the neuro attending and the surgical resident.

A split image of Arizona and Nicole, and Cristina and Dr Thomas in Grey’s Anatomy

Two of the most heartwarming scenes in the series happened between these two inside the infamous elevator.

Arizona & Nicole

Arizona Robbins’s friendships were all a tad unexpected.

Nicole’s nature was almost diametrically opposite to Arizona’s sunny personality.

Arizona and April talking on Grey’s Anatomy

Richard & Arizona

Beautiful friendships can emerge even when least expected.

The two supported each other as they both grappled their way through loneliness.

Richard was there forArizona throughout her custody battle with Callie over Sophia.

April and Owen side by side in Grey’s Anatomy

Richard and Arizona made unlikely friends but their friendship gave fans some heartwarming moments.

But in time, Cristina came to appreciate Thomas' old school techniques and he became her only friend.

His sudden death hurt Cristina more than she would ever admit.

Jo Wilson with Jackson in Greys

NEXT:Grey’s Anatomy Characters & Their Disney Counterparts

Callie sitting with Derek in conference room

Robbins and Altman talking in friendly manner

Derek breaking down and Bailey stopping the elevator

Arizona lying on the grass with Herman

April with Hunt and Riggs

Arizona and Richard talking in Grey’s Anatomy

Cristina standing beside Thomas in Grey’s Anatomy

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